Preterm and lowbirthweight infants are at elevated risk for death, neurodevelopmental disabilities, cognitive impairment, and behavioral disorders. More than 60% of mortality among infants without congenital or anatomical defects is attributable to plbw. The aim was to determine the association between maternal pd and lbw. Prevalence and predictors of periodontal disease among. Many risk factors have been identified including ethnicity, age, tobacco, and infection. Treatment of localized periodontal disease in pregnancy. Relationship between periodontal disease and preterm low. Govindaraju p, venugopal s, shivakumar ma, sethuraman s, ramaiah sk, mukundan s. Relationship between maternal periodontal disease and birth.
Scientists supported by the national institute of dental and craniofacial research, part of the national institutes of health, report in this weeks new england journal of medicine that pregnant women who received nonsurgical treatment for their periodontal, or gum, disease did not also significantly lower their risk of delivering a premature or lowbirthweight baby. Jun 24, 2014 the incidence of preterm low birth weight still prevails in developed as well as developing countries though the numbers may vary. Adult periodontal infection periodontitis affects up to 40% of women of reproductive age and is associated with preterm birth. Listing a study does not mean it has been evaluated by the u. Relationship between periodontal diseases and preterm birth. Maternal risk factors for ptb include young or advanced age, nutritional status, pre and antenatal care, smoking and alcohol consumption, and chronic inflammation and infections but the cause of spontaneous preterm labor remains unidentified in up to half of all cases. Pdf relationship between periodontal disease and preterm. Here we report a casecontrol study of 236 cases infants and weighing periodontitis to preterm birth and or low birth weight. Preterm delivery, or ptd, is the major cause of neonatal mortality and of nearly onehalf of all serious longterm neurological morbidity. The purpose of this study was to determine the association of maternal periodontitis with low birth weight lbw and preterm birth pb. Periodontitis and risk of preterm birth and low birthweight a metaanalysis. Periodontal disease and preterm delivery of lowbirthweight. Therefore, chemical mediators, principally crp, might be a plausible mediator of the association between periodontitis and adverse pregnancy outcomes.
The aim of this work was to assess the periodontal status of puerperae and determine its possible relationship with preterm low birth weight plbw delivery. Treatment of periodontal disease and the risk of preterm birth. Pdf association of periodontitis with preterm birth and low. For ten years, the incidence of preterm birth does not decrease in developed countries despite the promotion of public health programs. Association of periodontitis with preterm birth and low birth weight. Study finds periodontal treatment does not lower preterm. The studies focused on preterm birth, low birth weight and or preterm low birth weight and periodontitis. We know the best birth outcomes dont start in the delivery room. The sample included 88 ex pregnant women were seen at maternity hospitals of yazd, iran. Periodontal disease is a gramnegative anaerobic infection of the mouth that affects up to 90% of the population. Low birth weight, which affects the health of a newborn, is a result. Low birth weight lbw, defined as birth weight less than 2,500 g, continues to be a significant public health issue in both developed and developing countries. The association of periodontitis as risk factor for preterm birth has been in extensive.
Premature and low birth weight plbw infants are still 40. Low birth weight, defined as birth weight less than 2,500 g, continues to be a significant public health issue in both developed and developing countries. Birth and developmental correlates of birth weight in a sample of children with potential sensory processing disorder simone v gill1, teresa a maybenson2,3, alison teasdale2,3 and elizabeth g munsell1 abstract background. Preterm birth5 low birth weight newborns69 increased time to conception10 and premature rupture of membranes11 have been attributed to the presence of pd in pregnant women. Pdf association of periodontitis with preterm birth and. Relationship between periodontal parameters and plasma. Association between periodontitis in pregnancy and preterm or. These oral problems have been linked in many research studies to preeclampsia, low birth weight of the baby and premature birth. Preterm low birthweight and the role of oral bacteria. Expectant women should seek immediate treatment for periodontal disease in order to reduce the risk of prenatal and postnatal complications. Researches done by offenbacher et al at north carolina univeristy show that periodontitis gum disease may be linked to preterm pregnancies and low birth weight. Periodontal disease pd is a common infection in the community. Of the chosen studies, 29 suggested an association between periodontal disease and increased risk of adverse pregnancy outcome ors ranging from 1.
Periodontitis and prematurity are social diseases with common risk factors. Full term birth, low birth weight, periodontitis, preterm birth, risk factors how to cite this article. Periodontal status in mothers with preterm labor or low birth. Periodontal status in mothers with preterm labor or low. Relationship between periodontal disease and preterm low birth weight. An observational casecontrol study was performed in 1 puerperal women. American academy of periodontology statement on periodontal. Sixoupreterm low birth weight and maternal periodontal status. This obstetric complication is usually a direct result of preterm labour, in. Original article relationship between periodontal disease. Effects of periodontal treatment phase i on birth term and. Periodontitis and risk of preterm birth and low birthweight.
Low birthweight lbw is a major cause of infant mortality and morbidity around the world. Half of the mothers had low birth babies lbw birth weight below 2500g case group and the others had normal weight babies 2500g control group. Interrelation between periodontal disease and preterm birth. Considering the high prevalence of preterm birth ptb and low birth weight lbw and their complications as well as the role played by periodontal disease in their incidence and the lack of any report of periodontal therapy on these problems in iran, the goal of the present research was to determine the effects of periodontal treatment on plbw incidence among women with moderate or advanced. In spain the incidence of preterm births in 2005 was 7. Association between preterm and lowbirth weight with. The authors concluded that the periodontal health is an independent risk factor for premature birth babies and low birth weight babies. The aim of this study was to compare the periodontal status of mothers with preterm labor or low birth weight infants with mothers with term labor and normal birth weight infants. The periodontal disease index has an accuracy of 88. The periodontal disease as a risk factor for preterm birth. The aim was to determine whether clinical periodontal parameters are associated with plasma anti andor proinflammatory cytokines in pregnant woman with preterm birth pb or low birth weight lbw neonates.
This obstetric complication is usually a direct result of preterm labour, in which case it is. It has been suggested that periodontal disease is an important risk factor for preterm low birth weight plbw. Oral health inequities exist in many parts of the world, particularly in low resource countries. Preterm birth ptb is the major cause of perinatal morbidity and mortality as well as long term neurologic disability 1. The incidence of preterm low birth weight still prevails in developed as well as developing countries though the numbers may vary. Association of periodontal disease and preterm low birth. Treatment of periodontitis in pregnant women improves periodontal disease and is safe but does not significantly alter rates of preterm birth, low birth weight, or fetal growth restriction. Association between maternal periodontal disease and preterm. Relationship between periodontal diseases and preterm.
Preterm low birth weight plbw is a condition having tremendous financial impact on health care systems as well as the affected families. Periodontitis involves infection and progressive loss of the alveolar bone around the teeth. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Preterm birth and low birth weight are the leading perinatal problems world wide, and they account. Periodontal disease has been suggested to be an important risk factor for preterm low birthweight plbw. Dental college and hospital, amu, aligarh 202002, india. The aim was to determine whether clinical periodontal parameters are associated with plasma anti and or proinflammatory cytokines in pregnant woman with preterm birth pb or low birth weight lbw neonates.
Jul 12, 2016 the studies focused on preterm birth, low birth weight and or preterm low birth weight and periodontitis. According to the journal of the american dental association, increasing evidence suggests that maternal gingivitis inflammation of the gums and periodontitis inflammation and disease of the structures surrounding the teeth may be risk factors for preterm birth and. Research has linked periodontal gum disease to preterm birth and low birthweight babies at cigna, we have learned that with preventive care, many of the complications and costs associated with an unhealthy birth can be reduced and a lot of pain and suffering can be avoided. There is emerging evidence that periodontal disease is associated with an increased risk of cardiovascular disease 8,9, poor metabolic control of diabetes mellitus, and adverse pregnancy outcomes such as preeclampsia 11,12, low birth weight,14 and preterm birth 14,15 the existence of a relationship between periodontal disease and. Intrauterine growth restriction, low birth weight, and preterm birth. Materials and methods in this casecontrol study, 60 pregnant women. Research has linked periodontal gum disease to preterm.
Periodontal condition in pregnancy and low birth delivery incidence the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Here we report a casecontrol study of 236 cases infants weighing or 38 wks and weighing or 2500 g. Obstetricians knowledge of periodontal disease as a. The periodontal diseases are highly prevalent inflammatory and infectious diseases of tooth supporting. Periodontal condition in pregnancy and low birth delivery. High concentrations of these cytokines, in pregnant women, are responsible for rupture of the uterine membranes causing. To assess gynecologists knowledge of periodontal disease as a risk factor in plbw and their knowledge with regard to the oral. Birth and developmental correlates of birth weight in a. Here we report a casecontrol study of 236 cases infants 2500g control group. Adverse pregnancy outcomes and their association with maternal periodontitis.
Nine studies suggested that periodontal disease is a risk factor for low birth weight 1821, preterm birth 22, 23 or preterm low birth weight 2426. The study population comprised of women who delivered. Relationship between maternal periodontal disease and. About 11% of singleton births in the united states occur before 37 weeks of gestation, and the rate of premature delivery has increased during the past 15 years. The association of periodontitis as risk factor for pre. Periodontitis is a chronic inflammatory process with multifactorial etiology and adversely affects the outcome of pregnancy which becomes a major public health problem. Periodontal disease and pregnancy periodontal associates. Periodontitis as a risk factor for preterm lowbirth weight. Chicago november 7, 2006 research presented in a recent paper by michalowicz et al published in the new england journal of medicine nejm suggests that treatment of periodontitis in pregnant women improves periodontal health and is safe but does not significantly alter rates of preterm birth, low birth weight, or fetal growth restriction. Using a logistic regression model controlling for known preterm low birth weight risk factors, no periodontitis associated factors increased risk for preterm contractions or preterm low birth weight. Association between maternal periodontal disease and. One study from tanzania didnt find association between periodontal disease and adverse pregnancy outcomes 27 table 2, table 3. Evidence grade associating periodontitis to preterm birth. In 1996 periodontitis was proven to be a possible significant and independent risk factor of preterm birth of newborns with low body weight.
Periodontal disease as a risk factor in preterm low birth. This obstetric complication is usually a direct result of preterm birth ptb, in which case it is referred to as preterm delivery of low birth weight infants plbw. Obstetricians knowledge of periodontal disease as a potential risk factor for preterm delivery and low birth weight 250 braz oral res. Relationship between maternal periodontal disease and low. Of the selected studies, 9 implied an association between periodontal disease and increased risk of preterm birth, low birth weight and or preterm low birth weight outcome ors ranging from 2. It has been recently suggested that periodontal disease is an associated factor for prematurity and low birth weight. This casescontrol study was done on 70 women mean yrs.
297 1570 1421 948 151 214 994 472 411 1242 1232 1297 937 33 694 736 892 3 1522 1431 965 1162 868 641 1185 1340 1541 59 1531 1607 516 650 31 1073 1373 624 590 815 1421 499 185 343 622 109 466 571 1065 915 332